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Open Access

Cutaneous Adverse Reactions Associated with COVID-19 Vaccines

El Fatoiki FZ, Hali F, Idrissi OK, Meftah A and Chiheb SIdrissi OK (2022). Cutaneous Adverse Reactions Associated with COVID-19 Vaccines. J Corona Virus. 1(5); 1-4

Article Type: Case Series | Release date: 08 Apr 2022

1. Abstract1.1. Background: SARS-CoV-2 vaccination is crucial to reduce the risk of hospitalization, injury and mortality. However, several adverse cutaneous reactions can occur.1.2. Objectives: Objective was to collect and classify cutaneous side effects after SARS-CoV-2 vaccination in a Moroccan case series.1.3. Methods: A cross-sectional observational study among patients referred to the Dermatology Department of Ibn Rochd Hospital from February 2021 to November 2021. Patients of all ages vaccinated against COVID-19 who developed a skin manifestation within 1 month of administration of vaccine that had been approved by the national technical and scientific committee in Morocco (Sinopharm and Astrazeneca then Pfizer-BioNTech). Patients with explainable causes other than SARS-CoV-2 vaccination were excluded.

Open Access

Cutaneous Adverse Reactions Associated with COVID-19 Vaccines

El Fatoiki FZ, Hali F, Idrissi OK, Meftah A and Chiheb SIdrissi OK (2022). Cutaneous Adverse Reactions Associated with COVID-19 Vaccines. J Corona Virus. 1(5); 1-4

Article Type: | Release date: 08 Apr 2022

1. Abstract1.1. Background: SARS-CoV-2 vaccination is crucial to reduce the risk of hospitalization, injury and mortality. However, several adverse cutaneous reactions can occur.1.2. Objectives: Objective was to collect and classify cutaneous side effects after SARS-CoV-2 vaccination in a Moroccan case series.1.3. Methods: A cross-sectional observational study among patients referred to the Dermatology Department of Ibn Rochd Hospital from February 2021 to November 2021. Patients of all ages vaccinated against COVID-19 who developed a skin manifestation within 1 month of administration of vaccine that had been approved by the national technical and scientific committee in Morocco (Sinopharm and Astrazeneca then Pfizer-BioNTech). Patients with explainable causes other than SARS-CoV-2 vaccination were excluded.

Open Access

Safety of Zolindronic Acid in Osteoporosis: A Descriptive Cross Sectional Study

Naik M, Bhat T, Wani AA, Shafi A, Naqash

Article Type: Research Article | Release date: 11 Mar 2022

All bisphosphonates including zolindronic acid improve BMD in osteoporosis and decrease risk of spine, hip and other non-vertebral fractures significantly. The purpose of this study was to assess safety of zolindronic acid in osteoporosis in Kashmiri population. This was a descriptive cross sectional study conducted in tertiary care hospital of Kashmir valley. 77 pts were enrolled in the study with documented osteoporosis who received 5 mg zolindronic acid infusion with adequate prior hydration. All pts was followed for immediate adverse effects following infusion. Mild symptoms did occur in the form of fever, arthralgias, myalgias, muscle cramps and nausea. Majority of the symptoms subsided within two to three days of infusion. Our observations conclude that zolindronic acid is very much safe and fairly tolerated drug in osteoporosis.

Open Access

Management of Covid-19: An Illustrated Review from 2022 Updated NIH, IDSA and ICMCR Guidelines

Shafi A, Wani AA, Islam JU, Ovais Z

Article Type: Review Article | Release date: 11 Mar 2022

Coronavirus disease 2019 (COVID-19 has had a deleterious effect on the world’s demographics resulting in more than 3.8 million deaths worldwide, emerging as the most devastating global health crisis since the era of the influenza pandemic of 1918. The main concerns regarding the disease have been lack of specific antiviral therapies. Results from ongoing trials have given some promising results for the management of COVID-19 especially Molnupiravir, monoclonal antibodies, janus kinase inhibitors and remdesivir. This review article gives a comprehensive update on various pharmacological therapies in the light of recently published standard treatment guidelines for the management of COVID-19.

Open Access

Factors Influencing Colorectal Cancer Screening Uptake among Saudi Adults; A Cross-Sectional Study

Alghamdi TH

Article Type: Research Article | Release date: 07 Mar 2022

Introduction: Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020. 1-5 The most commonly recognized cancers are colorectal, lung, and breast cancers with colorectal cancer (CRC) ranks as the third most common in terms of new cases (1.93 million cases) in the world and is also the second most common cancer-related deaths (935 000 deaths).6-9 CRC screening can contribute to early diagnosis, lead to early treatment and better outcomes. Moreover, screening is proved to have sound contribution in the coming down of CRC incidence rate by 32% and reduction in mortality rate by 34% among adults aged 50 years and older.15-18

Open Access

Helmet Therapy in Childhood

Bittmann S, Luchter E, Moschüring-Alieva E, Bittmann L and

Article Type: Letter to the Editor | Release date: 07 Feb 2022

The term helmet therapy refers to conservative (non-surgical) treatment of infantile cranial deformities. Infantile cranial deformities can result from premature bony closure of the cranial sutures (premature suture synostoses) [1-5]. The incidence is reported to be about 1: 2,500 births [3,4]. Such early ossification can lead to quite different, sometimes bizarre skull shapes and also occurs in the context of circumscribed malformation syndromes (e.g. Crouzon syndrome, Apert syndrome).

Open Access

Helmet Therapy in Childhood

Bittmann S, Luchter E, Moschüring-Alieva E, Bittmann L and Villalon G

Article Type: Letter to the Editor | Release date: 04 Feb 2022

The term helmet therapy refers to conservative (non-surgical) treatment of infantile cranial deformities. Infantile cranial deformities can result from premature bony closure of the cranial sutures (premature suture synostoses) [1-5]. The incidence is reported to be about 1 : 2,500 births [3,4]. Such early ossification can lead to quite different, sometimes bizarre skull shapes and also occurs in the context of circumscribed malformation syndromes (e.g. Crouzon syndrome, Apert syndrome). In these syndromes, head deformities are present from birth and become more pronounced thereafter.

Open Access

Peptide LKEKK Reduces Acute and Chronic Skin Inflammation

Navolotskayaa EV*, Sadovnikova VB, Zinchenkoa DV, Zav’yalovb VP and Murasheva AN

Article Type: Research Article | Release date: 27 Dec 2021

We have established that the peptide LKEKK (Np5) corresponding to the sequence 16-20 of thymosin-α1 and to the sequence 131-135 of interferon-α2, in the concentration range 50 300 μg/ear reduces in a dose-dependent manner phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced skin edema in mice .Tested in parallel peptide with inverted sequence (iNp5, KKEKL, 150-300 μg/ear) was inactive, indicating high specificity of the Np5 action. In the concentration range of 5 20 μM Np5 significantly decrease the TNF-α-induced production by normal human keranocytes of pro-inflammatory mediators IL-6 and IL-1β. Thus, Np5t has a pronounced anti-inflammatory activity in vivo and in vitro.

Open Access

Impact of Plasmodium Falciparum Malaria on Liver and Red Blood Cell

Gregorio Rangel, Ratana Leksomboon, Surasak Wanram Mohd, Ridzuan Mohd, Abd Razak4 and Joao Martins5

Article Type: Review Article | Release date: 15 Dec 2021

Malaria remains one of the greatest public health challenges worldwide, particularly in tropical and sub-tropical countries. Estimates about 212 million and 429.000 death per year worldwide. The liver and red blood cell (RBC) are the organ that has clearly changed in the early stages of infection. The aim of this study was to elucidate the inflamed sinusoidal area showing the change of liver morphology in severe Plasmodium falciparum (P. falciparum) malaria infection and red blood cell anatomical changes. P. falciparum malaria invasion associated with endothelial activation and expression of adhesion molecules. Some infected RBCs can be eliminated by the host immune system. However, some carry on infection which leading to severe malaria. Decrease deformability of erythrocyte infected by malaria parasites may play a role of enrichment in the liver. The different sizes and shapes of infected RBC in the liver were resulted diversity morphological of RBCs and their function in the infected organs.

Open Access

Investigating the Effect of Time Spent in Moisture on the Rate of Mycelial Colony Growth of Pleurotus Ostreatus (Common Oyster Mushroom) in a Nutrient Controlled Spawn

Rangan A

Article Type: Brief Scientific Report | Release date: 08 Dec 2021

How does changing the level of moisture given to a sample of Pleurotus ostreatus over time change the rate of growth of the mycelial colony?PERSONAL ENGAGEMENTThe kingdom of fungi has always enticed me. When compared to other organisms, fungi prove to be unique and diverse, almost alien in nature. Yet, fungi have existed for longer than humans,and will likely persist beyond our reign. I was motivated to choose this experiment over others simply due to my love of all thing’s fungi.

Open Access

Science Education Graduates’ Difficulties in Conducting Undergraduate Research

Marshall James P Dantic and Maria Florida B Mariano

Article Type: Research Article | Release date: 20 Nov 2021

The researcher's role is shaping policies and communicating with the public. The purpose of this study is to enlighten the students who have difficulties in conducting their own research. The study involved 20 SEGs. Comprehensive sampling was implemented. Data gathering done online. Findings revealed that among the five phases, Phase 2 (proposal writing) and Phase 4 (data analysis and interpretation) were considered difficult for the graduates wherein a significant difference when respondents are grouped according to specialization. Thematic analysis was done to treat the qualitative data. Three themes emerged in the category, other difficulties experienced. These include research- related difficulties; respondent- related difficulties; and advisee and adviser-related difficulties. As to suggestions to overcome the difficulties, three themes were generated [1]. observance of time management [2], use of cognitive approach in research; and [3] establishment of good communication between advisee and adviser. The study concluded that the SEGs faced difficulty in the five phases. The study recommends a workshop which accentuates conceptualization, techniques in reviewing related literature, and analyzing data may be spearheaded by the college. Finally, advisee-adviser mentoring program may be institutionalized to produce high quality researches geared towards improving teacher education in the country.

Open Access

A Case Report On Baclofen Induced Acute Encephalopathy in Esrd Patient

S Haja Sherief, Basil Sunny, Merin Cherian and Aysha Nashva

Article Type: Case Report | Release date: 08 Nov 2021

Baclofen is a commonly prescribed muscle relaxant, also used for hiccups and muscle spasm. It is usually administered orally or delivered intrathecal. Baclofen is extensively eliminated through kidneys as unchanged drug, hence renal compromised patients are more prone to risk of accumulation and toxicity. Neurological manifestations are highly prevalent in such patients. Here we delineate a case report on baclofen induced encephalopathy in end stage renal disease (ESRD) patient, which was resolved with the help of prompt hemodialysis.

Open Access

Esophageal bezoar on peptic stenosis in a 7-year-old child

Bakkali O, Meskini T, Berrani H, Sabib M, Ettair S and Mouane N

Article Type: Case Report | Release date: 22 Oct 2021

The term bezoar refers to foreign bodies found in the digestive tract. It results in a stagnation of ingested non-digestible substances. We report a case of an esophageal bezoar collected in the pediatric gastroenterology department of the children's hospital in Rabat- MOROCCO. This observation of an esophageal bezoar, the first in our institution, to our knowledge, confirms the rarity of the pathology. 7-year-old child, taken by his parents to the children's hospital of the university hospital in Rabat for total aphagia. His history shows: psychomotor retardation, followed for 2 years for peptic esophagitis complicated by peptic stenosis.

Open Access

Consumer buying Behaviour on Ayurvedic Product in Dindigul District of Tamil Nadu

Mohamed Ali, A Ponmani, M Kalishwari,J Balamurugan,S Ramesh

Article Type: Research Article | Release date: 18 Oct 2021

In this article discussed on Ayurvedic preparations and treatment are most trustable approach to fix the unidentified and serious maladies without having any symptoms additionally it is financially perception strategies so individuals are eager to receive to fix their sicknesses and looking for the ayurvedic items in the marketing strategies. The consumer purchasing decision to ayurvedic items are chosen by the buyer as indicated by their necessities and climatic conditions. In this specific situation, it is comprehended that strategies that are consolidated to advance the ayurvedic items which pulls in the buyers to settle on buy choices for the kind of items in Dindigul Distrit of Tamil Nadu. It is com- prehended that Ayurvedic items are extemporized the wellbeing by reviving the resistant arrangement of the individuals in normal manners so as the examination infers that individuals are continuously utilizing the ayurvedic items to empower their solid life design by devouring the ayurvedic items.

Open Access

Leucopenia Induced by Tamoxifen in a Breast Cancer Patient: A Case Report Al-Bairmany

Al-Bairmany YSR

Article Type: Case Study | Release date: 18 Oct 2021

A 28-year-old woman was diagnosed with invasive ductal carcinoma of the left breast. The final tumor stage was pT2 pN3. She received adjuvant chemotherapy with four cycles of Adriamycin and Cyclophosphamide every three weeks, followed by four cycles of Taxol every three weeks. After chemotherapy, she received the standard dose of adjuvant radiotherapy (RT= 50 Gy/15 fractions) for three weeks.

Open Access

Lead Induced Abdominal Colic in a Teenage Female

Mukul Rastogi and Jagdish RK  

Article Type: Case Report | Release date: 11 Oct 2021

Abdominal pain is a very common symptom in gastroenterology practice but sometimes it become very tedious to find the exact etiology behind it. A through history taking and understanding of the possible medical causes is paramount in narrowing down the differential diagnosis and thus accurate treatment. We present the case of a 14 -year -old girl diagnosed with lead poisoning highlighting that rather than occupational or environmental contamination, it was consumption of ayurvedic medication which was the prime reason for her elevated Blood Lead Levels (BLL).

Open Access

Onychomycosis Treatment with Fotona Laser

Arellano-Huacuja A*, Arellano-Montalvo D and Arellano-Montalvo A

Article Type: Research Article | Release date: 11 Oct 2021

Onychomycosis is a fungal infection of the nails. It does not usually cause discomfort, but it alters the aesthetics of the affected nails and, if not treated in time, it can become chronic and spread. The cause of onychomycosis are fungi of the dermatophyte type.

Open Access

Striking Biochemical Markers in Laboratory Diagnosis for People in COVID-19 Pandemic

Inan K, Muge MK and Erdi AT

Article Type: Research Article | Release date: 11 Oct 2021

During the Coronavirus disease 2019 (COVID-19) outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the importance of markers used to evaluate the severity of disease in humans may differ from others. In this review, the biochemical markers that attract much attention in COVID-19 outbreak were tried to be evaluated simply.

Open Access

Lifestyle Changes For People With Non Communicable Diseases In The COVID-19 era: A Survey Conducted Around The World

Liba H and Belahsen R

Article Type: Research Article | Release date: 11 Oct 2021

In addition to its economic, psychological and social impact, the lockdown imposed in the era of the coronavirus pandemic (COVID-19) is a potentially risky situation for people with chronic diseases. In order to highlight the importance of food in the response to this virus, the objectives of this study were to explore the changes that accompanied the lockdown imposed by governments, as a protective measure to limit the spread of the COVID-19 virus.

Open Access

Covid-19 Vaccines, Immunity, And Effect On Children

Simonian M

Article Type: Editorial | Release date: 04 Oct 2021

The Oxford/AstraZeneca and Johnson & Johnson vaccines use adenoviral technology which is different than the mRNA technology used by Pfizer and Moderna.

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