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Journal of Neuropsychiatry and Neurodisorders

Exploring The Role and Effect of Memantine and its Correspondents for the Treatment of Alzheimer’s Disease

Abstract

Alzheimer disease is senile decay of neurons. The hallmark of pathophysiology of AD disease has two pivotal features example- extracellular beta amyloid deposition and intracellular tau hyper phosphorylation. Memantine is an effective and approved compound in the treatment of Alzheimer disease. Due to its profound pharmacological activity, proper physic-chemical properties and well-defined chemical structures allow it to inhibit the excitatory effect of glutamine. Meta-analysis data provides us information about its effectiveness and its ease of synthesis. Memantine has no serious side effects due to which it can be a safe bet in treatment of Alzheimer disease.

 

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